Diffusion At A Glance

Founded: 2001
Ownership: Privately held

Company Co-founders:
David Kalergis, JD, MBA
John Gainer, PhD

Headquarters:
2020 Avon Court, #4
Charlottesville, VA 22902
USA

Diffusion Pharmaceuticals is a clinical-stage company developing first-in-class drugs which target the numerous unmet medical needs characterized by hypoxia at the cellular level. These proprietary small molecules work by a novel mechanism of action that enhances the diffusion of oxygen selectively to hypoxic tissue. Potential breakthrough clinical applications include oncology, cardiovascular diseases, stroke and respiratory disorders. Diffusion’s lead program is the use of TSC in the treatment of solid cancerous tumors. A phase I/II clinical study of TSC dosed concomitantly with radiation and chemotherapy in newly diagnosed GBM patients will begin patient recruitment in 2011. Diffusion Pharmaceuticals, which is privately held, is located in Charlottesville, Virginia.